carbomer 940 hydrogel enhances capillary blood flow and tissue viability in a skin burn wound

Carbomer 940 Hydrogel Enhances Capillary Blood Flow and Tissue Viability in a Skin Burn Wound

Objective- To evaluate the application of Carbomer 940 hydrogel on saving zone of stasis in skin burn wound. Design- Experimental study Animals- Twenty rats. Procedures- After shaving the backs, a ‘comb burn’ was contacted bilaterally on the dorsum of the rats 0.5 cm lateral and parallel to the midline by usin...

Skin capillary blood flow in scleroderma.

Skin blood flow was measured by the clearance of radioactive xenon ((133)Xe) injected intracutaneously in eight patients with scleroderma and nine control subjects under conditions of controlled temperature and humidity. Scleroderma patients, on being cooled 1 hr at 18 degrees C, had a rate constant of (133)Xe clearance from the dorsal finger skin which was 0.04 +/-0.07 min(-1) (mean +/-SD), co...

Gelam (Melaleuca spp.) Honey-Based Hydrogel as Burn Wound Dressing

A novel cross-linked honey hydrogel dressing was developed by incorporating Malaysian honey into hydrogel dressing formulation, cross-linked and sterilized using electron beam irradiation (25 kGy). In this study, the physical properties of the prepared honey hydrogel and its wound healing efficacy on deep partial thickness burn wounds in rats were assessed. Skin samples were taken at 7, 14, 21,...

Assessment of tissue viability with blood flow measurements.

Topical Simvastatin Enhances Tissue Regeneration in Full-thickness Skin Wounds in Rat Models

Wounds and wound healing have always been one of the most important subjects that experimental researches were dedicated to. Simvastatin has been used for long as a common lipid lowering agent which was reported to have some pleiotropic effects such as antioxidation, anti-inflammation and immunomodulation. In this study we aimed to determine the effect of simvastatin on wound healing process in...

Topical Simvastatin Enhances Tissue Regeneration in Full-thickness Skin Wounds in Rat Models

Wounds and wound healing have always been one of the most important subjects that experimental researches were dedicated to. Simvastatin has been used for long as a common lipid lowering agent which was reported to have some pleiotropic effects such as antioxidation, anti-inflammation and immunomodulation. In this study we aimed to determine the effect of simvastatin on wound healing process in...